As a leading Chinese manufacturer of UF membranes and filtration systems, we specialize in high-performance, cost-effective ultrafiltration solutions tailored for TCM extraction, clarification, and sterilization. Our self-produced UF membranes ensure superior quality, fast production cycles, and competitive pricing, making them ideal for pharmaceutical companies seeking reliable and efficient filtration.
Introduction
In the biopharmaceutical industry, ensuring the purity, safety, and efficacy of medicinal products is paramount. Traditional Chinese Medicine (TCM), particularly herbal injections and concentrated extracts, requires advanced filtration technologies to remove bacteria, endotoxins, and macromolecular impurities while retaining active pharmaceutical ingredients (APIs). Ultrafiltration (UF) membranes have emerged as a critical solution for TCM processing, offering high selectivity, scalability, and compliance with GMP standards.
As a leading Chinese manufacturer of UF membranes and filtration systems, we specialize in high-performance, cost-effective ultrafiltration solutions tailored for TCM extraction, clarification, and sterilization. Our self-produced UF membranes ensure superior quality, fast production cycles, and competitive pricing, making them ideal for pharmaceutical companies seeking reliable and efficient filtration.
Challenges in TCM Processing
TCM formulations, especially injectable solutions, face several purification challenges:
1. Bacterial and Endotoxin Contamination – Microbial and pyrogen removal is critical to meet pharmacopeia standards (e.g., Chinese Pharmacopoeia, USP).
2. Macromolecular Impurities – Polysaccharides, proteins, and tannins can affect drug stability and safety.
3. Active Ingredient Loss – Traditional filtration methods (e.g., centrifugation, chemical precipitation) may lead to API degradation or waste.
4. Process Efficiency – Slow filtration and frequent membrane fouling increase production costs.
Our UF membranes address these challenges effectively, providing a closed, continuous, and scalable purification process.
Why Choose Our Ultrafiltration Membranes for TCM?
1. High Selectivity for Effective Ingredient Retention
Our UF membranes (MWCO: 1,000–100,000 Da) are optimized to:
Remove bacteria, viruses, and endotoxins while preserving small-molecule active compounds (e.g., flavonoids, alkaloids).
Reject colloids, proteins, and polysaccharides that cause turbidity or adverse reactions.
Improve drug clarity and stability, ensuring compliance with injection-grade purity requirements.
2. Superior Fouling Resistance & Long Service Life
Hydrophilic modified PVDF/PES membranes reduce clogging from TCM’s sticky colloids and polyphenols.
Asymmetric pore structure enhances flux stability, reducing cleaning frequency.
Chemical-resistant to acids, alkalis, and ethanol (common in TCM extraction).
3. High-Efficiency Processing – Faster Than Traditional Methods
Cross-flow filtration minimizes concentration polarization, allowing continuous operation.
Automated systems reduce labor costs and human error.
30–50% faster processing compared to ceramic membranes or depth filtration.
4. Cost-Effective Production (Made in Our Own Factory)
Vertical integration (from polymer selection to membrane casting) ensures low production costs.
No middlemen – Direct factory pricing benefits bulk buyers.
Customizable pore sizes and modules (hollow fiber, flat sheet, spiral-wound) for different TCM applications.
5. Short Lead Time & Reliable Supply
In-house manufacturing allows 2–4 week delivery (vs. 8+ weeks for imported brands).
Large inventory of standard UF modules for urgent orders.
Applications in TCM Pharmaceutical Production
1. Purification of Herbal Injections
Removal of heat sources (endotoxins) and microorganisms to meet sterile injection standards.
Case Study: A customer producing astragalus injections achieved >99.9% endotoxin clearance using our 50 kDa UF membrane, with API recovery >95%.
2. Concentration of Active Extracts
Replace vacuum evaporation – Our UF system precisely concentrates ginsenosides, paclitaxel, or berberine without thermal degradation.
Benefits: 40% lower energy costs, higher product yield.
3. Decolorization & Clarification
Eliminates tannins and pigments from extracts (e.g., licorice, salvia miltiorrhiza).
Output: Crystal-clear solutions ready for further processing (e.g., spray drying).
4. Recycling of Solvents/Water
UF + RO integration allows ethanol/water reuse in extraction, cutting waste disposal costs.
Conclusion: Optimize Your TCM Production with Our UF Solutions
For pharmaceutical companies seeking high-purity, efficient, and affordable ultrafiltration, our membranes offer an unmatched combination of performance and value. Whether for herbal injections, extract refinement, or solvent recovery, we provide:
✅ GMP-compliant, endotoxin-free filtration
✅ Higher yield & lower operating costs
✅ Fast delivery & dedicated technical service
Contact us today to discuss your TCM project requirements – let our UF membranes enhance your product quality and profitability!
Q&A
Q: What's the smallest particle UF can remove?
A: 0.01 micron (10 nanometers) - removes most bacteria and viruses.
Q: Can UF operate without electricity?
A: No, requires power for pumps and controls (but low energy use).
Q: How quickly does UF produce clean water?
A: Immediate filtration - no settling time required.
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If you want to get more details about filter and filtration equipment, you can send E-mail to filter01@lefilter.com. You can consult our professional engineer and specialized sales team with leave a message in below form. We will contact with you ASAP. You also can visit our factory in Henan China.