JHM UF-2860-2880 Industrial Circulating Water Ultrafiltration membrane Replacement

Introduction

In the critical field of hemodialysis, the efficiency and safety of ultrafiltration (UF) membranes directly impact patient outcomes. As a specialized Chinese manufacturer with full in-house production, we deliver high-performance UF membranes that excel in biomedical filtration, particularly for renal replacement therapies. Our membranes are engineered to provide exceptional toxin clearance, biocompatibility, and operational reliability, making them ideal for dialysis machines, hemodiafiltration (HDF), and critical care applications.

With vertically integrated manufacturing, we offer unbeatable cost efficiency, rapid prototyping, and scalable production—ensuring medical device manufacturers receive premium-quality membranes without long lead times.

The Critical Function of Ultrafiltration in Modern Dialysis

Hemodialysis replicates the kidney’s filtration process by removing metabolic waste, excess electrolytes, and fluids from patients with end-stage renal disease (ESRD). The ultrafiltration membrane acts as the semi-permeable barrier that enables:

1. Selective removal of uremic toxins (e.g., urea, creatinine, phosphate)

2. Controlled fluid extraction to prevent pulmonary edema

3. Preservation of albumin and vital blood components

Our asymmetric hollow-fiber UF membranes are optimized for high solute permeability, low thrombogenicity, and mechanical robustness, ensuring consistent performance in clinical settings.

Key Advantages of Our Hemodialysis-Optimized UF Membranes

1. Advanced Polymer Science for Enhanced Biocompatibility

We utilize modified polyarylethersulfone (PAES) and polyvinylpyrrolidone (PVP)-blended membranes to achieve:

✔ Minimal platelet adhesion – Reducing clotting risks during dialysis

✔ Superior hydrophilicity – Preventing protein fouling for sustained flux rates

✔ Reduced complement activation – Enhancing patient tolerance

2. Precision Engineering for Optimal Clearance Rates

Tunable pore structures (MWCO 20–60 kDa) for targeted toxin removal

High ultrafiltration coefficients (Kuf) enabling efficient fluid management

Low extractable levels – Complying with ISO 10993-5 cytotoxicity standards

3. Rigorous Durability for Demanding Clinical Use

Resistant to oxidative cleaning agents (e.g., hypochlorite, hydrogen peroxide)

Stable under pulsatile blood flow conditions

Validated for steam and gamma sterilization

4. Streamlined Supply Chain for Medical Device Partners

By controlling raw material sourcing, fiber spinning, and module assembly, we eliminate supply chain delays. Our just-in-time production model supports:

✔ Customized membrane configurations (fiber diameter, packing density)

✔ Small-batch feasibility studies for R&D teams

✔ Bulk orders with accelerated delivery

Expanding Applications in Extracorporeal Blood Treatment

Our UF membranes are integral to next-generation therapies, including:

🔹 High-Volume Hemodiafiltration (HV-HDF) – Combining convection and diffusion for superior middle-molecule clearance

🔹 Pediatric Dialysis – Miniaturized modules with enhanced safety profiles

🔹 Bioartificial Kidney Development – Supporting hybrid membrane-cell systems

Commitment to Global Regulatory Excellence

We manufacture under ISO 13485-certified processes with:

1. FDA 510(k)-compliant material formulations

2. Full traceability from polymer to final module

3. Batch-specific validation reports (including endotoxin testing per USP <85>)

Partner with a Dedicated Medical Filtration Innovator

For dialysis device OEMs and therapeutic apheresis companies, our ultrafiltration membranes represent the optimal balance of clinical efficacy and manufacturing economics. Backed by 16+ years of membrane expertise, we empower partners to:

✅ Reduce production costs without sacrificing quality

✅ Accelerate time-to-market for novel dialysis technologies

✅ Address global shortages with reliable volume production

Contact our technical team to request performance data sheets, prototyping samples, or OEM collaboration proposals!

Q&A

Q: Does UF require chemical additives?

A: Only for cleaning, not during normal operation.

Q: What is the operating pH range?

A: Usually pH 2-11, depending on membrane material.

Q: How to store UF membranes?

A: Keep them wet in preservative solutions when not in use.